Do you have experience in small molecule, preclinical drug development and want to play a larger, more impactful role in a smaller, but well financed and resourced company? Our San Diego client has $120M Series B funding, a recent, successful IPO and an active early pipeline focused on rare and degenerative diseases. They are looking for a highly motivated and experienced preclinical scientist to support nonclinical in vivo and in vitro studies in late-stage research and early development. The ideal person will have prior experience in preclinical pharmacology including design/oversight of ADME/PK studies, toxicology, and IND-enabling programs. S/he will have a passion and drive for translational medicine and motivation to produce rigorous experimental data to inform drug development. In this role you will:
- Design and execute preclinical and translational studies necessary to support regulatory filings and prepare high quality documentation, including study reports and regulatory submissions on aggressive timelines.
- Support development of therapeutic opportunities through preclinical proof-of-concept and target validation in models of rare diseases, including outsourcing in vivo pharmacology, PK and biodistribution studies and identifying specialized CROs and/or collaborators with appropriate expertise.
- Work closely with basic research scientists and R&D project teams to generate study designs, gain scientific and budgetary approval, execute studies and present study reports and recommendations to relevant groups.
To be considered you will need:
- An advanced degree with broad experience in preclinical pharmacology and IND-enabling safety programs. BS degree candidates with significant preclinical development and leadership experience will be considered. 5-10 years industry experience with direct responsibility for the design, execution, and documentation of regulated studies.
- Direct experience and understanding of biopharmaceuticals and drug development.
- Strong scientific track record and interpersonal and communication skills; the ability to influence project direction in a cross-functional team environment.
- The ability to take initiative and work well in a small, close-knit team environment.
- Experience in rare diseases is preferred.
Southern California residents are preferred. You must be a N. American resident with current, unrestricted work authorization or TN visa eligible.
To apply for this position, confidentially email us here.