Our client, a multinational therapeutic company, has a leadership opportunity for a talented downstream process development scientist experienced in biologics, especially vaccines. This person will lead both people and projects in a company with strong career development. Multiple projects from an expanding pipeline will keep you learning and growing, personally and professionally. You will work cross-functionally with upstream process development, regulatory, manufacturing, even commercial development. You will contribute to INDs by writing the CMC portions and be involved in tech-transfer for clinical production. You may also lead, train, and mentor junior scientists at all levels. Other duties include:

  • Evaluating incoming new projects from the research team
  • Evaluate, develop and optimize the process parameters for downstream purification.
  • Troubleshoot issues related to the process and product.
  • Use DOE software to design the experiment, analyze the results
  • Write technical reports and transfer methods to clinical or commercial manufacturing
  • Guide/train junior level scientists

To be considered, you will need:

  • A PhD with 5+ years experience or an MS degree with a minimum of 15 years’ relevant industry experience
  • Master or Ph.D of Science/engineering in Biology, chemistry, chemical engineering, or related discipline
  • Downstream experience is necessary including Chromatography Purification and Diafiltration/Ultrafiltration experience
  • Design of Experiment (DoE) experience
  • Scale down/scale up knowledge
  • Strong trouble shooting and data analysis skills
  • Good writing skills
  • Good communication skills

Preferred Experience includes

  • Downstream process development of viruses or VLPs
  • Experience with IND and BLA is preferred
  • Engineering knowledge/hands-on experience troubleshooting equipment issues
  • Upstream process knowledge
  • Protein chemistry knowledge
  • Good aseptic technique

To apply for this position, confidentially email us here.